Substrate: Intersectin 1 (Adapter molecule)
Seq-ID: Q15811 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16777   SOS1_HUMAN
MINT-64267   SMRC2_HUMAN
MINT-65948   DYN1_HUMAN
MINT-2516855   DYN2_HUMAN
MINT-7046364   CBL_HUMAN
MINT-7302469   DYN1_MOUSE
MINT-7302524   SYNJ1_HUMAN
MINT-7302543   WASL_HUMAN
MINT-7302563   CBL_MOUSE
MINT-7302595   SOS1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
calcium ion binding,
protein binding		 cell junction,
cytosol,
lamellipodium,
synapse,
synaptosome,
endomembrane system		 induction of apoptosis by extracellular signals,
apoptosis,
synaptic vesicle endocytosis,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 313 YIPPSFRRVRSGSGISVISST - 18669648
HTP
1.00
 - -
0.46
 --
S 315 PPSFRRVRSGSGISVISSTSV - 18669648
HTP
1.00
 - -
0.44
 --
S 901 SAFTPATATGSSPSPVLGQGE - 18669648
HTP
0.82
 - -
0.74
 --
S 902 AFTPATATGSSPSPVLGQGEK - 18669648
HTP
1.00
 - -
0.75
 --
S 904 TPATATGSSPSPVLGQGEKVE - 15302935
HTP
1.00
 - -
0.75
 --
S 904 TPATATGSSPSPVLGQGEKVE - 18669648
HTP
1.00
 - -
0.75
 --
S 986 STSMDSGSSESPASLKRVASP - 18669648
HTP
0.16
 - -
0.64
 --

Substrate: Intersectin 1 (Adapter molecule)
Seq-ID: ENSP00000370719 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
Rho guanyl-nucleotide exchange factor activity,
calcium ion binding,
protein binding		 cell junction,
cytosol,
lamellipodium,
synapse,
synaptosome,
endomembrane system		 induction of apoptosis by extracellular signals,
apoptosis,
synaptic vesicle endocytosis,
regulation of Rho protein signal transduction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 559 NDQLKQVQQNSLHRDSLVTLK - 17081983
HTP
 - - -
0.42
 - low

Substrate: Intersectin 1 (Adapter molecule)
Seq-ID: Q9Z0R4 [Mus musculus]
Download:fasta csv
Interaction Network(s): -
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-16627   DYN1_MOUSE
MINT-4789804   EPN1_MOUSE
MINT-5206832   EPS15_MOUSE
MINT-7042065   CBL_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
kinase activator activity,
Rho guanyl-nucleotide exchange factor activity,
calcium ion binding,
protein binding		 cell junction,
lamellipodium,
synapse,
endocytic vesicle,
synaptosome,
endomembrane system		 positive regulation of protein kinase B signaling cascade,
negative regulation of neuron apoptosis,
regulation of Rho protein signal transduction,
small GTPase mediated signal transduction,
endocytosis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 313 YIPPSFRRVRSGSGMSVISSS - 17242355
HTP
1.00
 - -
0.55
 --
S 315 PPSFRRVRSGSGMSVISSSSV - 15345747
HTP
1.00
 - -
0.53
 --
S 318 FRRVRSGSGMSVISSSSVDQR - 17242355
HTP
1.00
 - -
0.58
 --
S 334 SVDQRLPEEPSSEDEQQPEKK - 17242355
HTP
0.00
 - -
0.90
 --
S 335 VDQRLPEEPSSEDEQQPEKKL - 15345747
HTP
0.30
 - -
0.89
 --
S 335 VDQRLPEEPSSEDEQQPEKKL - 17242355
HTP
0.30
 - -
0.89
 --
S 335 VDQRLPEEPSSEDEQQPEKKL - 17203969
HTP
0.30
 - -
0.89
 --
S 895 AFTPATATGSSPSPVLGQGEK - 15345747
HTP
1.00
 - -
0.76
 --
S 895 AFTPATATGSSPSPVLGQGEK - 17242355
HTP
1.00
 - -
0.76
 --
S 897 TPATATGSSPSPVLGQGEKVE - 15345747
HTP
1.00
 - -
0.76
 --
S 897 TPATATGSSPSPVLGQGEKVE - 17242355
HTP
1.00
 - -
0.76
 --
T 970 KLISGPVRKSTSIDTGPTESP - 17114649
HTP
0.10
 - -
0.60
 --
T 977 RKSTSIDTGPTESPASLKRVA - 17242355
HTP
0.00
 - -
0.66
 --
S 1130 WFPANYVKLLSPGTSKITPTE - 16452087
HTP
1.00
 - SH3
0.33
 --

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